Women who experience menopause before the age of 40 may face a significantly higher lifetime risk of developing heart disease, according to a new study.
The research, published in JAMA Cardiology, found that natural premature menopause was associated with about a 40 per cent increase in the lifetime risk of coronary heart disease compared with menopause occurring at the usual age.
Researchers analysed data from more than 10,000 postmenopausal women aged 55 to 69 who participated in six long-term U.S. studies conducted between 1964 and 2018.
None of the women had coronary heart disease at the start of the study, and all had experienced natural rather than surgical menopause.
Over the follow-up period, researchers recorded more than 1,000 cases of coronary heart disease, including heart attacks and deaths related to heart disease.
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After adjusting for established risk
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